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Which one of the following conditions is usually regarded as multifactorial?
 
A. Fragile X syndrome
B. ischaemic heart disease
C. Marfan syndrome
D. neurofibromatosis type 2
E. maturity-onset diabetes of the young (MODY)
 
 
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Answer B.
See chapters 1, 12 and 14 of Essential Medical Genetics 6th edition for further explanations.